Can foreigners receive stem cell therapy in Japan?

Yes. Regenerative medicine is self-pay and does not require Japanese nationality or Japanese insurance. You will need to provide the medical records the provider asks for, complete a consultation and tests, and plan for two trips: one for cell collection and one for treatment.

How can I check that a clinic offers regenerative medicine legally?

A legitimate provider has filed a regenerative medicine provision plan with the MHLW and holds a plan number. Ask the clinic for its plan number or look it up on the MHLW's public list of providers. XIUYI can share the plan numbers of the providers we work with.

What is the difference between stem cell therapy and stem cell conditioned medium?

Stem cell therapy infuses cultured cells and is regulated under the regenerative medicine law. Conditioned medium (supernatant) is the culture fluid left over from growing stem cells; it contains no cells and is mostly used in drips or aesthetic injections. Their uses, prices and regulatory status differ.

How does NK cell therapy work?

Your own blood is drawn, the NK and other immune cells in it are cultured in a processing facility, and they are infused back intravenously several weeks later. A doctor decides whether it suits you based on your consultation and test results.

Can a clinic guarantee results?

No, and none should promise them. Results vary from person to person. XIUYI helps you understand the options, checks provider registration and arranges visits and communication; diagnosis and treatment are the responsibility of the provider and doctor.

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Regenerative medicine in Japan: stem cell therapy and NK cell therapy

We connect you with providers offering consultations and services in regenerative medicine.

Why choose this service

Clear consultation and assessment steps
Review of provider registration
Coordination of eligibility and timing

Service details

Discuss options and eligibility
Contact providers and arrange visits
Coordinate communication around treatment

Regenerative medicine · Cost guide

Stem cell therapy cost in Japan →

Stem cell infusions and NK cell therapy are self-pay treatments in Japan. Using our partner clinic’s price sheet, this guide breaks down the total cost, course prices and what to check on a quote before you pay.

Regenerative medicine · Patient guide

Stem cell treatment in Japan for international patients →

Foreign nationals can receive self-pay regenerative medicine in Japan. This guide walks through checking that a clinic is compliant, the records to prepare, the trip schedule and follow-up after you return home.

Regenerative medicine · Immune cell therapy guide

NK cell therapy in Japan →

NK cell therapy cultures immune cells from your own blood and returns them to your body. Using our partner clinic’s price sheet, this guide covers cost, the process, how it relates to cancer treatment and what to check.

How Japan regulates regenerative medicine

Japan's Act on the Safety of Regenerative Medicine has applied since 2014. Before a clinic can offer stem cell or immune cell treatments on a self-pay basis, the treatment is classified as Class I, II or III by risk, reviewed by a certified regenerative medicine committee, and filed with the Ministry of Health, Labour and Welfare (MHLW) as a provision plan with its own plan number. Treatments using your own adipose-derived stem cells are generally Class II; treatments using your own immune cells are generally Class III. XIUYI only works with providers that have filed a plan. We can share the plan number on request, and you can check it against the MHLW's public list.

Treatments you can ask about

Our partner providers offer intravenous infusion of adipose-derived mesenchymal stem cells, intra-ovarian stem cell injection, NK cell and combined immune cell therapy, and autologous fibroblast transplantation. All of them use your own cells: fat, blood or a small skin sample is collected, the cells are cultured in a cell processing facility, and then infused or injected. A doctor decides whether a treatment suits you after a consultation and blood tests.

Process and time in Japan

1. Tell us what you are looking for online; we help organise your medical records and check-up reports. 2. First visit: initial consultation and regenerative medicine consultation, with blood tests if the doctor considers them necessary. 3. Fat, blood or skin is collected. 4. Cell culture usually takes several weeks. 5. A second visit for the infusion or injection, followed by follow-up. Most treatments therefore need two trips to Japan; the provider sets the exact schedule. XIUYI coordinates appointments, Chinese/English/Japanese interpreting, transfers and accommodation.

Costs

Regenerative medicine is self-pay and not covered by Japan's public health insurance. Stem cell infusions are priced in three tiers by the number of cells per session, and the per-session price falls as the course gets longer. The table shows the starting price of each treatment.

Reference prices

Item	JPY · tax incl.
Initial consultation	5,500
Regenerative medicine consultation	11,000
Regenerative medicine blood test	33,000
Adipose-derived mesenchymal stem cells · IV infusionStem cells are taken from your own fat, cultured and returned by drip. Three tiers by cell count; longer courses cost less per session. 100M-tier courses are valid for 2 years; in the 150M and 200M tiers, buying 2+ sessions first stores seed cells free for 3 years, 4+ for 5 years.	From 3,355,000
NK immune cellsYour own blood is drawn, its immune cells cultured and returned. A 3-session course comes with 3 NMN or 5-ALA drips.	From 770,000
High-activity combined immune cell therapyYour own blood is drawn, its immune cells cultured and returned. A 3-session course comes with 3 NMN or 5-ALA drips.	From 880,000
Intra-ovarian stem cell injectionStem cells are taken from your own fat, cultured and injected into the ovaries; 50 million+ cells per session. Buying 2+ sessions first stores seed cells free for 3 years.	From 3,520,000
Autologous fibroblast transplantA small piece of your own skin is taken, its fibroblasts are cultured, then injected where needed. Harvest and culture are paid first; a positive infection screen adds 33,000.	From 594,000

Prices come from our partner providers' price lists and are reference prices in JPY, tax included. The final treatment, number of sessions and fees follow the doctor's assessment and a formal quote.

Medical institutions require appointments. Select plans and items for consultation; XIUYI confirms the institution and availability after discussing your needs. Availability is subject to confirmation, and selecting items does not confirm a booking.

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Regenerative medicine

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A younger look

Items: 1

Autologous fibroblast transplant

A small piece of your own skin is taken, its fibroblasts are cultured, then injected where needed. Harvest and culture are paid first; a positive infection screen adds 33,000.

Skin harvest + initial culture (required first)594,000Transplant 1 cc330,000Transplant 4 cc759,000Transplant 8 cc1,518,000Transplant 10 cc1,897,500Cell storage, 1 year198,000

First step

Regenerative medicine consultation and assessment

Reference fees are ¥5,500 for an initial consultation and ¥11,000 for a regenerative medicine consultation. A blood test, if requested by the physician, is an additional ¥33,000.

Need help choosing an option?

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Frequently asked questions

Can foreigners receive stem cell therapy in Japan?: Yes. Regenerative medicine is self-pay and does not require Japanese nationality or Japanese insurance. You will need to provide the medical records the provider asks for, complete a consultation and tests, and plan for two trips: one for cell collection and one for treatment.
How can I check that a clinic offers regenerative medicine legally?: A legitimate provider has filed a regenerative medicine provision plan with the MHLW and holds a plan number. Ask the clinic for its plan number or look it up on the MHLW's public list of providers. XIUYI can share the plan numbers of the providers we work with.
What is the difference between stem cell therapy and stem cell conditioned medium?: Stem cell therapy infuses cultured cells and is regulated under the regenerative medicine law. Conditioned medium (supernatant) is the culture fluid left over from growing stem cells; it contains no cells and is mostly used in drips or aesthetic injections. Their uses, prices and regulatory status differ.
How does NK cell therapy work?: Your own blood is drawn, the NK and other immune cells in it are cultured in a processing facility, and they are infused back intravenously several weeks later. A doctor decides whether it suits you based on your consultation and test results.
Can a clinic guarantee results?: No, and none should promise them. Results vary from person to person. XIUYI helps you understand the options, checks provider registration and arranges visits and communication; diagnosis and treatment are the responsibility of the provider and doctor.

Specific options, eligibility and fees depend on the provider’s assessment and formal quote. Medical institutions require appointments; XIUYI confirms the institution and availability after consultation.

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