Regenerative medicine · Cost guide
Stem cell therapy cost in Japan
Stem cell infusions and NK cell therapy are self-pay treatments in Japan. Using our partner clinic’s price sheet, this guide breaks down the total cost, course prices and what to check on a quote before you pay.
Prices and facts checked: November 4, 2026
What the total cost is made of
Regenerative medicine is self-pay care outside Japan’s public health insurance. The total splits into medical fees paid to the clinic and the non-medical costs of travelling to Japan. Most treatments need two trips — one to collect cells, one to receive them — so plan travel costs for both.
- Consultation and tests: first visit, regenerative medicine consultation and, when the doctor requires it, a blood test
- Cell collection and culture: fat, blood or skin is collected and cultured in a cell processing facility
- Administration: infusion or injection; the price depends on sessions and cells per session
- Non-medical: flights and accommodation, medical interpreting, transfers
Reference prices at our partner clinic
| Item | Details | Reference price (JPY, tax incl.) |
|---|---|---|
| First visit | — | 5,500 |
| Regenerative medicine consultation | Suitability check | 11,000 |
| Regenerative medicine blood test | When the doctor requires it | 33,000 |
| Adipose-derived mesenchymal stem cell infusion | 100M+ cells per session | from 3,355,000 |
| NK immune cell therapy | 1 / 3 sessions | 770,000 / 2,310,000 |
| Highly active combined immune cell therapy | 1 / 3 sessions | 880,000 / 2,640,000 |
| Intra-ovarian stem cell injection | 50M+ cells per session | from 3,520,000 |
| Autologous fibroblast transplant | Skin harvest + initial culture (required first) / 1 cc transplant | 594,000 / from 330,000 |
| Stem cell conditioned medium drip | Contains no cells; 1 ampoule | 55,000 |
Tax-inclusive reference prices from our partner clinic’s price sheet. Final items, sessions and costs follow the doctor’s assessment and a formal quote.
Stem cell infusion prices by course
Autologous adipose-derived stem cell infusions come in three tiers by cells per session; longer courses cost less per session.
| Sessions | 100M+ per session | 150M+ per session | 200M+ per session |
|---|---|---|---|
| 1 session | 3,355,000 | 3,465,000 | 4,400,000 |
| 2 sessions | 6,380,000 | 6,578,000 | 8,360,000 |
| 3 sessions | 9,020,000 | 9,350,000 | 12,000,000 |
| 4 sessions | 11,330,000 | 11,770,000 | 14,960,000 |
| 6 sessions | — | 16,610,000 | 21,120,000 |
| 8 sessions | — | 20,790,000 | 26,400,000 |
| 10 sessions | — | 25,987,500 | 33,000,000 |
| 12 sessions | — | 31,185,000 | 39,600,000 |
JPY, tax incl. The 100M+ tier is offered up to 4 sessions.
For example, one 150M+ session costs JPY 3,465,000, while the 12-session course (JPY 31,185,000) works out at about JPY 2,598,750 per session; at 200M+ a single session is JPY 4,400,000 and about JPY 3,300,000 per session over 12. 100M+ courses are valid for 2 years. For 150M+ and 200M+ courses, buying 2+ sessions up front includes 3 years of free seed-cell storage, and 4+ sessions includes 5 years.
More cells do not necessarily mean a better result. Cell count is one feature of a preparation; discuss quality, route of administration and clinical evidence with the doctor rather than comparing price per 100 million cells.
Worked totals
These are calculations from the price sheet, not a patient’s case. The doctor decides which tests and how many sessions are needed.
- Two stem cell infusions at 100M+: first visit 5,500 + consultation 11,000 + blood test 33,000 + 2-session course 6,380,000 = JPY 6,429,500 in medical fees
- NK immune cell therapy, 3 sessions: first visit, consultation and blood test 49,500 + 3-session course 2,310,000 = JPY 2,359,500 in medical fees (the course includes 3 NMN or 5-ALA drips)
Flights and accommodation for two trips, medical interpreting and transfers come on top. Ask for these to be itemised separately from medical fees.
Why prices differ so much between clinics
Two clinics can quote several times apart for a “stem cell infusion”. The main differences are:
- Cell source: your own cells (autologous) or a donor’s (allogeneic)
- Culture and quality-testing process, and how cells are collected
- Cells per session and number of sessions
- Hospital stay or observation, and follow-up after you return home
A higher price does not mean a better outcome. Compare cell quality, clinical evidence, number of sessions and the whole service side by side.
What to check on a quote
- Which of collection, culture, quality testing, transport and storage the culture fee covers
- How you are charged if the cells fail to grow or do not meet release criteria
- What a deposit is for and when it is refundable
- Whether follow-up visits and tests are included
- Whether medical fees are listed separately from interpreting, transfers and accommodation
- What happens if you notice no effect — results are not guaranteed, so read the contract terms first
Confirm all cost terms in writing before paying. Necessary fees that were never explained should not appear after treatment.
Does insurance cover it?
Self-pay stem cell infusions and NK cell therapy are not covered by Japan’s public health insurance. Japan has approved some regenerative medical products under the PMD Act, but each approval is limited to a specific product, indication and conditions of use; it does not mean general self-pay stem cell infusions are approved. Ask your own insurer whether overseas medical cover applies.
Frequently asked questions
How much does stem cell therapy cost in Japan?
At our partner clinic, autologous adipose-derived stem cell infusions start at JPY 3,355,000 per session for 100M+ cells (tax incl.). A first visit (JPY 5,500), consultation (JPY 11,000) and, when required, a blood test (JPY 33,000) are extra. The total depends on cell count and sessions and is fixed by a formal quote after the doctor’s assessment.
How much is NK cell therapy?
NK immune cell therapy is JPY 770,000 per session or JPY 2,310,000 for a 3-session course (tax incl.), which includes 3 NMN or 5-ALA drips.
Do I pay if the cell culture fails?
A refund cannot be promised across the board. How a failed culture, or cells that miss release criteria, are charged depends on the contract signed beforehand — confirm it in writing before paying.
Can I get a refund if the treatment does not work?
Medical results are not guaranteed, so refunds depend on the contract and what was explained. Neither “full refund” nor “no refund” can be promised in advance.
Why is conditioned medium so much cheaper than stem cell therapy?
Stem cell therapy administers the cultured cells themselves and is regulated under Japan’s regenerative medicine law. Conditioned medium is the liquid left from culturing stem cells; it contains no cells and has a different use and legal status. Drips start at JPY 55,000 per ampoule.
Before a quote, tell us about your records and goals
Send us your medical records, check-up results and the treatments you are considering. We organise the questions for the clinic and coordinate the visit and a formal quote.
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